Dupuytren's disease in an infant.
نویسندگان
چکیده
Dupuytren's disease of the hand has only been rarely reported in children and is rarer still in infants. We report a case in a six-month-old infant who required surgery when aged ten months. Histology confirmed the diagnosis of Dupuytren's disease.
منابع مشابه
Areview of Dupuytren\'s contracture in 43 hands: assessment of the nature and result after fasciectomy
Abstract Background: Dupuytren's disease is a fibroproliferative disorder of the palmar fascia that can result in disabling contractures of the digits. When function is impeded or deformity is disabling, surgical intervention can be considered, wherein a major problem is recurrence ( reported up to 74%). Although, the disease occurs predominantly in men of northern European, there are ver...
متن کاملGeneration of contractile force by cultured Dupuytren's disease and normal palmar fibroblasts.
Contractile fibroblasts are believed to be responsible for palmar fascia contracture in Dupuytren's Disease. An in vitro collagen lattice model was used to examine the contractile properties of Dupuytren's fibroblasts from 10 patients undergoing partial fasciectomy, and palmar fascia fibroblasts from 6 patients undergoing carpel tunnel release. Dupuytren's and palmar fascia fibroblasts cultured...
متن کاملAssociation of Morbus Ledderhose with Dupuytren's contracture.
BACKGROUND Fibromatous nodules in the sole of the foot are often called Ledderhose disease. It is a benign nodular formation in the plantar aponeurosis, typically at the distal medial border. A lump forms and it can be a few centimeters in diameter. It is frequently seen as an isolated disease, but a relationship to Dupuytren's has been noted in some patients. METHODS The study was a part of ...
متن کاملDupuytren's disease susceptibility gene, EPDR1, is involved in myofibroblast contractility.
BACKGROUND Dupuytren's Disease is a common disorder of the connective tissue characterized by progressive and irreversible fibroblastic proliferation affecting the palmar fascia. Progressive flexion deformity appears over several months or years and although usually painless, it can result in a serious handicap causing loss of manual dexterity. There is no cure for the disease and the etiology ...
متن کاملCalcium-dependent signaling in Dupuytren's disease.
BACKGROUND Previous studies suggest that Dupuytren's disease is caused by fibroblast and myofibroblast contractility. Cell contractility in smooth muscle cells is caused by calcium-dependent and calcium-independent signaling mechanisms. In the calcium-dependent pathway, calcium/calmodulin activates myosin light chain kinase (MLCK). In this study, the effects of calcium/calmodulin inhibition wit...
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ورودعنوان ژورنال:
- The Journal of bone and joint surgery. British volume
دوره 87 1 شماره
صفحات -
تاریخ انتشار 2005